וְאֶת־עֵשָׂ֖ו שָׂנֵ֑אתִי וָאָשִׂ֤ים אֶת־הָרָיו֙ שְׁמָמָ֔ה וְאֶת־נַחֲלָת֖וֹ לְתַנּ֥וֹת מִדְבָּֽר׃
But Esau I hated, And made his mountains a desolation, And gave his heritage to the jackals of the wilderness.
Read kabbalistic (mystical) interpretation of Malachi 1:3: and classical mystical sources.