וַיִּמְאֲס֣וּ אֶת־חֻקָּ֗יו וְאֶת־בְּרִיתוֹ֙ אֲשֶׁ֣ר כָּרַ֣ת אֶת־אֲבוֹתָ֔ם וְאֵת֙ עֵֽדְוֺתָ֔יו אֲשֶׁ֥ר הֵעִ֖יד בָּ֑ם וַיֵּ֨לְכ֜וּ אַחֲרֵ֤י הַהֶ֙בֶל֙ וַיֶּהְבָּ֔לוּ וְאַחֲרֵ֤י הַגּוֹיִם֙ אֲשֶׁ֣ר סְבִֽיבֹתָ֔ם אֲשֶׁ֨ר צִוָּ֤ה יְהוָה֙ אֹתָ֔ם לְבִלְתִּ֖י עֲשׂ֥וֹת כָּהֶֽם׃
and they rejected His statutes, and His covenant that He made with their fathers, and His testimonies wherewith He testified against them; and they went after things of nought, and became nought, and after the nations that were round about them, concerning whom the LORD had charged them that they should not do like them;
Pat Lechem
that the remembrance of the affairs of this world and the ways of its inhabitants be desolate and absent from his heart. Or, the intent is that one is astonished and wonders in his heart from the world and its inhabitants, how they busy themselves without a [true] purpose, and "follow the vanities, etc." (Melachim II 17:15) and to abhor their affairs, as in (Daniel 8:27) "I was appalled by the vision; it was beyond understanding".