Quoting Commentary for II Kings 5:24

וַיָּבֹא֙ אֶל־הָעֹ֔פֶל וַיִּקַּ֥ח מִיָּדָ֖ם וַיִּפְקֹ֣ד בַּבָּ֑יִת וַיְשַׁלַּ֥ח אֶת־הָאֲנָשִׁ֖ים וַיֵּלֵֽכוּ׃

And when he came to the hill, he took them from their hand, and deposited them in the house; and he let the men go, and they departed.

Ibn Ezra

The condition known as p…s has to do with that which is excreted from a part of the body that is normally covered — hence, [the Hebrew vulgarity in the text] is spelled with the letters -p-l, from “mound [Hebrew: ofel]” [II Kings 5: 24].
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