Дварим 22:9 Комментарий: Rashi, Ibn Ezra, Rashbam & Rabbeinu Bahya

כלאים [THOU SHALT NOT SOW THY VINEYARD] WITH DIVERSE KINDS OF SEEDS — i.e. wheat and barley together with kernels of grapes with one and the same hand-throw (Berachot 22a; Kiddushin 39a; Chullin 82b).

The consequence lest it be consecrated is conditional on you must not sow … with diverse seeds. The Spaniard Menaḥem ben Ya‘aqov ibn Saruq has explained in his Textbook that the word consecrated comes from the triliteral root q-d-sh, on account of the seeds’ intermixture with one another.

תקדש, is prohibited just as קדשים, sacred things are prohibited to most people.

פן תקדש LEST IT BECOME קדש — Take it as the Targum does: lest it become unclean (unfit for use); to anything for which a man has repugnance to come into contact with, be it on account of its sublimity as, for instance, holy things, or be it on account of some bad quality, as, for instance, something that is forbidden, the term קדוש is appropriate, as, in the latter sense, e.g., (Isaiah 65:5) “Come not near to me for I make thee קדוש".