תּלמוד אויף בראשית 25:23

וַיֹּ֨אמֶר יְהוָ֜ה לָ֗הּ שְׁנֵ֤י גיים [גוֹיִם֙] בְּבִטְנֵ֔ךְ וּשְׁנֵ֣י לְאֻמִּ֔ים מִמֵּעַ֖יִךְ יִפָּרֵ֑דוּ וּלְאֹם֙ מִלְאֹ֣ם יֶֽאֱמָ֔ץ וְרַ֖ב יַעֲבֹ֥ד צָעִֽיר׃

און גאָט האָט צו איר געזאָגט: צװײ אומות זײַנען אין דײַן לײַב, און צװײ פֿעלקער װעלן זיך פֿון דײַנע אינגעװײד צעשײדן, און אַ פֿאָלק פֿון אַ פֿאָלק װעט זײַן שטאַרקער, און דער עלטערער װעט דינען דעם ייִנגערן.

Jerusalem Talmud Sotah

10Gen. rabba 20(12), 45(14), 63(8). Rebbi Joḥanan in the name of Rebbi Eleazar ben Rebbi Simeon: We do not find that the Omnipresent talked to a woman, except only to Sarah. But is there not written11Gen. 3:16.: “To the woman He said: I shall increase,” etc.? Rebbi Jacob of Kefar Ḥanin12Elsewhere he is called “from Kefar Ḥanan”. said, through an interpreter13Adam is addressed by the Eternal in 3:9, the woman in 3:13, the snake in 3:14.. But is there not written14Gen. 25:23.: “The Eternal said to her, two peoples are in your womb”? Rebbi Abba bar Cahana said, the Word fell to her15A word about her fell to a prophet (in the opinion of Gen. rabba, Sem ben Noah.). Rebbi Biri said, how many weaver’s shuttles! The Holy One, praise to Him, desires to hear the talk of the just women: “He said no, but you laughed.16The only time we find a mention of God addressing a woman directly it is about an unimportant matter.”
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Megillah

R. Nahman b. Yitzchak derived the same lesson from here: “And the one nation shall be stronger than the other nation” (Genesis 25:23).
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Berakhot

The school of R. Ishmael taught : Why are they called "cucumbers" [kishshuim] ? Because they are injurious [kashim] to the body like swords. But it is not so ! For lo, it is written, "And the Lord said unto her, Two nations are in thy womb" (Gen. xxv. 23) — read not goyim "nations," but geim "lords"; and Rab Judah said in the name of Rab: These are Antoninus and Rabbi from whose table radish, lettuce and cucumbers were never absent either in Summer or Winter !
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