Kommentar zu Bereschit 19:25

'ויהפוך את הערים וגו AND HE OVERTHREW [THOSE CITIES] etc. — The four cities were situated on one rock and He turned them upside down, as it is said, (Job 28:9) “He putteth forth His hand upon the flinty rock [and overturneth the mountains by the roots]” (Genesis Rabbah 51:4).

ויהפוך, the earth as well as its inhabitants underwent a total chemical transformation being turned into brimstone and fire, similar to what David means in Psalms 105,29 “He turned their waters into blood.” The dew that rose from the earth prior to sunrise turned into salt. Compare Deut. 29,22 גפרית ומלח שרפה כל ארצה, meaning that the moisture descended back onto earth but this time mixed with solid burned particles.

ויהפך, He turned these cities and the valley from having been most fruitful to becoming most desolate. According to Job 28,6-8 the region had not only been good pasture land but its soil had yielded gold, gemstones, etc. The sulfur and brimstone which made up most of this rain made the earth forever incapable of producing crops or other matters of value to mankind. We know that even birds shun that region.