Musar zu Dewarim 28:65

Anger is a bad quality and just as scurvy is a disease of the body so is anger a disease of the soul. And our sages have said : "He who loses his temper is exposed to all the torments of hell" (Nedarim 22a) as it is said : "Therefore, remove vexation from thy heart, and put away evil from thy flesh" (Eccl. 11:10), and by "evil" they mean Gehenna, as it is said : "The Lord hath made everything for His own purpose, Yes, even the wicked for the day of evil" (Prov. 16:4). And not only this but an angry man is afflicted with piles as it is said : "The Lord will give you there an anguished heart and eyes that pine, and a despondent spirit" (Deut. 28:65). What ill is it that dims the eyes and pains the soul— Surely you will say "Piles".