עַל־כֵּן֙ יַֽעֲזָב־אִ֔ישׁ אֶת־אָבִ֖יו וְאֶת־אִמּ֑וֹ וְדָבַ֣ק בְּאִשְׁתּ֔וֹ וְהָי֖וּ לְבָשָׂ֥ר אֶחָֽד׃
Therefore shall a man leave his father and his mother, and shall cleave unto his wife, and they shall be one flesh.
Rashi on Genesis
על כן יעזב איש THEREFORE A MAN LEAVETH — The Divine Spirit says this, thus prohibiting immoral relationship to the “Sons of Noah” also (Sanhedrin 57b).
Ramban on Genesis
THEREFORE SHALL A MAN LEAVE HIS FATHER AND HIS MOTHER, AND SHALL CLEAVE TO HIS WIFE. The Divine Spirit says this, thus prohibiting immoral relationships to “the sons of Noah.”372See above, Note 222.
Sforno on Genesis
על כן, seeing that on this first occasion G’d had aimed to make Adam’s wife as much part of him as possible, so that he even used Adam’s personal body as Chavah’s basic skeleton,