Commentary for Exodus 30:32

לא ייסך with two “yods” has the meaning “he shall not do something” (i. e. it is 3rd person masc. sing. Kal), similar to ייטב in (Deuteronomy 6:18) “that it may be well (ייטב) with thee”.

קדש הוא, "it is holy." This refers to the quantity being sacred. Even if the oil would be compounded of materials not listed here, i.e. something altogether profane, a combination of components in the quantities mentioned here would make it "sacred" in the sense of "forbidden." Anyone concocting such a mixture would be as guilty as a layman offering a total offering or sin-offering on his own behalf. If all such a person wanted to do was to train himself in the art of making such compositions, or in order to donate it to the community, this is permissible as we learned in Keritut 5.

ובמתכנתו, corresponding to the proportions of the various ingredients listed here.