וַיֹּ֖אמֶר מֶ֣ה עָשִׂ֑יתָ ק֚וֹל דְּמֵ֣י אָחִ֔יךָ צֹעֲקִ֥ים אֵלַ֖י מִן־הָֽאֲדָמָֽה׃
Y él le dijo: ¿Qué has hecho? La voz de la sangre de tu hermano clama á mí desde la tierra.
Or HaChaim
ויאמר השם לא ידון רוחי. G'd said: "My spirit will not abide in man permanently." This verse needs someone to explain it. Our sages have given numerous explanations to it without explaining the plain meaning of the verse. It appears that the Torah wishes to tell us that a change occurred in G'd's dealing with man. During the lifetime of Adam, Eve, Cain and Abel, G'd personally had rebuked man for any misdemeanour. When man's deeds became increasingly repulsive to G'd, He decided not to deal with them on such an intimate basis.
English Explanation of Mishnah Sanhedrin
For so have we found it with Cain that murdered his brother, for it says, “The bloods of your brother cry out” (Gen. 4:10). It doesn’t say, “The blood of your brother”, but rather “The bloods of your brother” meaning his blood and the blood of his descendants. Another saying is, “The bloods of your brother” that his blood was cast over trees and stones. The mishnah proves its point, that killing one person is like killing all of his future descendants, by using a midrash on God’s words to Cain after he killed Abel, “The bloods of your brother call out”. The midrash is based on the fact that God uses the plural “bloods” instead of blood. This is to teach us that Cain killed not only Abel but all of Abel’s descendants as well. The mishnah then proceeds with an additional interpretation of “the bloods”. According to this interpretation God uses the plural because Abel’s blood was strewn in many places. This last note is obviously a late gloss interpolated into the mishnah.
Or HaChaim
ויהי בהיותם בשדה. It was when they were both in the field. We need to know why the Torah wanted us to know that what follows occurred in the field. Besides, why did the Torah have to mention that "Cain arose?" It would have sufficed to simply state that Cain killed Abel! Furthermore, why did G'd have to ask Cain where his brother Abel was? Why was Cain foolish enough to tell the One who knows everything that he did not know where his brother was? After all, who would be aware of G'd's supervising everything that occurs on earth if not the people with whom G'd had communicated directly such as Adam, Eve, Cain, etc.? Why did Cain add the gratuitous and provocative remark: "Am I my brother's keeper?" Why did G'd have to mention (verse 10) that Abel's blood cried out to Him "from the earth?" Besides, what was the nature of that outcry? Why did G'd curse the earth in addition to the murderer? What harm did it do for the earth to have swallowed Abel's blood? The alternative would have been for the dogs to lick it up. Did earth not act very properly by covering up the blood of the dead? G'd's words almost defy our understanding.