עָרֵ֥י קָדְשְׁךָ֖ הָי֣וּ מִדְבָּ֑ר צִיּוֹן֙ מִדְבָּ֣ר הָיָ֔תָה יְרוּשָׁלִַ֖ם שְׁמָמָֽה׃
No te aires, oh SEÑOR, sobremanera, ni tengas perpetua memoria de la iniquidad: he aquí mira ahora, pueblo tuyo somos todos nosotros.
Rashi
Desert and wasteland Jerusalem, called ‘wasteland,’ and Zion, called ‘desert,’ they shall rejoice over the downfall of the mighty of the heathens and Persia ([Manuscripts yield:] of Edom and Bozrah). ([The Warsaw edition reads:] the mighty of Seir (and Bozrah).)
Rabbeinu Bahya
A Midrashic view cited in Shemot Rabbah 24,4: “This was a place where the Israelites were anxious to place flags in rows upon rows. Another explanation: the desert of Shur is a euphemism for the Jewish people prior to their receiving the Torah. As long as the Torah had not been given the entire world was comparable to a wilderness. Once the Torah was given it was transformed into “Shur” i.e. a (protective) wall. Rabbi Yehudah son of Rabbi Seymon quoted G’d as saying that in the future He would do the same for Zion. Whereas in Isaiah 64,9 Zion was described as a wilderness, it would become a protective wall as prophesied in Zecharyah 2,9 “I shall become a wall of fire (for Zion) surrounding it and I will glory inside it.”
Or HaChaim
ונתתי את עריכם חרבה, "and I will turn your cities into ruins." The Torah means that not only will our cities no longer be a model for other nations but that they will be inferior to the civilisation of the Gentile nations. This is a source of great distress. Isaiah had this in mind when he described the cities of Yehudah and Zion as being turned into a desert (Isaiah 64,9) unless the Jewish people would mend their ways.