La Genèse 22:6 Midrash : Mekhilta DeRabbi Yishmael, Pirkei DeRabbi Eliezer, Midrash Tanchuma Buber & Bereshit Rabbah

(Ibid. 24) "And it was in the morning watch": We find that the prayers of the righteous are heard in the morning. The "morning" of Abraham — (Genesis 22:3) "And Abraham rose early in the morning, etc." The "morning" of Isaac — (Ibid. 9) "and both of them went together, etc." — and both had risen early in the morning.

He took the wood and placed it upon the back of his son Isaac, and he took the fire and the knife in his hand, and they went both of them together. Isaac said to his father: O my father! Behold the fire and the wood, where is the lamb for the burnt offering? He replied to him: My son! Thou art the lamb for the burnt offering, as it is said, "And Abraham said, God will provide for himself the lamb" (Gen. 22:8).

(Gen. 22:6:) THEN ABRAHAM TOOK [THE WOOD FOR THE BURNT OFFERING AND SET IT UPON HIS SON ISAAC]. To whom was Isaac comparable? To one who (after being condemned to death) was going out to be burned with his wood on his shoulders. ¹⁷⁰Cf. Gen. R. 56:3.