מדרש על יהושע 20:8

(Numb. 19:3 cont.:) AND HE (Eleazar) SHALL SLAUGHTER IT (i.e., Edom-Rome) IN HIS PRESENCE (i.e., of the Holy One). Thus it is stated (in Is. 34:6): FOR THE LORD HAS A SACRIFICE IN BOZRAH,¹³⁴See Makk. 12a, according to which prince of Edom erred in seeking asylum in Bozrah instead of Bezer, which is listed in Deut. 4:43 and Josh. 20:8 as a city of refuge. A GREAT SLAUGHTER IN THE LAND OF EDOM (i.e., Rome). R. Berekhyah (interpreting the text differently) said: THE SLAUGHTER OF A GREAT ONE (i.e., Rome's guardian spirit) IN EDOM.