Midrash su Giobbe 24:13

The Nephilim were on the earth in those days…. these were the mighty men that were of old, the men of renown (Gen. 6:4). This verse informs us that the Nephilim would gaze upon the sun and the moon and perform feats of magic through them, as it is said of them: These are of them that rebel against the light (Job 24:13). The word these in both verses indicates that the Nephilim were the mighty men and were cruel and rebellious and performed acts of magic. Yet they said unto God: Depart from us, for we desire not knowledge of Thy ways. What is the Almighty, that we should serve Him? And what profit should we have, if we pray unto him? (Job 21:14–15).

Rabbi Simeon said: From Seth arose and were descended all the generations of the righteous. From Cain arose and were descended all the generations of the wicked, who rebel and sin, who rebelled against their Rock, and they said: We do not need the drops of Thy rain, neither to walk in Thy ways, as it is said, "Yet they said unto God, Depart from us" (Job 21:14).