זָכָ֥ר וּנְקֵבָ֖ה בְּרָאָ֑ם וַיְבָ֣רֶךְ אֹתָ֗ם וַיִּקְרָ֤א אֶת־שְׁמָם֙ אָדָ֔ם בְּי֖וֹם הִבָּֽרְאָֽם׃ (ס)
남자와 여자를 창조하셨고 그들이 창조되던 날에 하나님이 그들에게 복을 주시고 그들의 이름을 사람이라 일컬으셨더라
Ramban on Genesis
AND HE BLESSED THEM. This means that He gave them the power of procreation, to be blessed forever with very many sons and daughters. The intent is to state that begetting offspring comes as a blessing of G-d, for Adam and Eve were not born but were created from nothing and they were blessed to do so [to beget offspring].
Radak on Genesis
זכר ונקבה...ויברך אותם, the blessing, mentioned already in 1,28 consisted of his ability to reproduce, fill the earth and conquer it. If man was equipped to conquer others, he must certainly be able to conquer the evil urge within himself.
Rabbeinu Bahya
זכר ונקבה בראם, “He created them male and female.” The words “male and female” refer to the שכל, intelligence, and נפש, emotional life-force, respectively. These two components are major factors in the acquisition of wisdom, the body is quite peripheral, serving only as receptacle, a repository for the former.