וּנְתָנָ֛ם יְהוָ֥ה אֱלֹהֶ֖יךָ לְפָנֶ֑יךָ וְהָמָם֙ מְהוּמָ֣ה גְדֹלָ֔ה עַ֖ד הִשָּׁמְדָֽם׃
네 하나님 여호와께서 그들을 네게 붙이시고 그들을 크게 요란케 하여 필경은 진멸하시고
Rashbam
פן תורש, so that you will not be driven from the land due to the famine. The root ירש of which the word תורש is a derivative occurs in the sense of disposing, expelling in Deut. 9,3 והורשתם ואבדתם מהר, “you will expel them and destroy them quickly.” It also occurs in a slightly different form in Deut. 7,23 פן תוקש בו, “so that you will not be trapped by it.” There the root is יקש. [as long as two of the root letters match there is a strong conceptual linkage between the two roots. Ed.]
Midrash BeChiddush
16. Their legs were afflicted with hemorrhoids טְּחֹרִ֔ים. This is what happens to those who travel during the summer months - they develop a type of dry scab between their thighs that is painful. The Egyptians were afflicted with these. This appeared not only on the thighs but on the opening of the rectum where they became hemorrhoids. That is why in the Reproofs (In Exodus and Deuteronomy) boils of Egypt are connected with scabs and itches. There is no doubt that swelling on the legs was a natural occurrence among those who travel. They continue to grow until they become a plague. Thus, the sages state in the Mekhilta: "Confounding" is plague, viz. (Deut 7:23) "And He will confound them with great confusion until they are destroyed."202See Mekhilta DeRebbe Yishmael 14:24 Thus, there are plagues here: scabs between one’s thighs, hemorrhoids in one’s rectum, some of which were opened and some of which were closed, some on the inside of the rectum and some on the outside, and all of them infected. There are also dry legs and bubonic plague203Literally it says the plague of the plague. This is a surmise on my part. .