ייִדישער מחשבֿה אויף בראשית 3:15

וְאֵיבָ֣ה ׀ אָשִׁ֗ית בֵּֽינְךָ֙ וּבֵ֣ין הָֽאִשָּׁ֔ה וּבֵ֥ין זַרְעֲךָ֖ וּבֵ֣ין זַרְעָ֑הּ ה֚וּא יְשׁוּפְךָ֣ רֹ֔אשׁ וְאַתָּ֖ה תְּשׁוּפֶ֥נּוּ עָקֵֽב׃ (ס)

און אַ פֿײַנטשאַפֿט װעל איך מאַכן צװישן דיר און צװישן דער פֿרױ, און צװישן דײַן זאָמען און צװישן איר זאָמען; ער װעט דיך טרעפֿן אין קאָפּ, און דו װעסט אים טרעפֿן אין טריט.

For the Perplexed of the Generation

It also seems that there was also a divine step taken to connect humanity with all other living things. This was indeed the best thing from the standpoint of divine perfection, that in the end, man will yearn for the highest ethical nobility, that he will demand of himself his obligation towards all creations, his friends in creation and in life. But for man [himself], he could not find a companion opposite him. Man is not prone to actualize his humanity if he has an urge to understand that he has a partnership and brotherly connection with animals that are more lowly than him. Therefore, he was disconnected from them through that slumber, where it was revealed to him that his bond of companionship is different than all other living things, and the small bond he had with the most devious of all animals, [the snake,] caused man a moral downfall to the point that he would only be saved from it through the placing of animosity between the two species, (Genesis 3:15) “I will place animosity between you and the woman, between your offspring and her offspring.” But when the Torah gave permission to eat meat, it when on at length, (Deuteronomy 12:20) “When your soul desires to eat meat...” as a boundary, as if to say, "When your natural ethical state does not abhor the eating of living things like you would abhor the eating of human meat..." That’s why the Torah doesn’t have to explicitly prohibit cannibalism, for [man] has already acquired the correct natural idea in this, and the Torah doesn’t need to give an exhortation, just like it doesn’t need to specify good and bad character traits, which are embedded, and familiar. But when the time comes of an ethical state of disgust for meat because of a natural repulsion to it, there will be no “urge of your soul to eat meat”, and it would [theoretically] be prohibited to eat.
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Guide for the Perplexed

It is especially of importance to notice that the serpent did not approach or address Adam, but all his attempts were directed against Eve, and it was through her that the serpent caused injury and death to Adam. The greatest hatred exists between the serpent and Eve, and between his seed and her seed; her seed being undoubtedly also the seed of man. More remarkable still is the way in which the serpent is joined to Eve, or rather his seed to her seed; the head of the one touches the heel of the other. Eve defeats the serpent by crushing its head, whilst the serpent defeats her by wounding her heel. This is likewise clear.
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