עַל־כֵּן֙ יַֽעֲזָב־אִ֔ישׁ אֶת־אָבִ֖יו וְאֶת־אִמּ֑וֹ וְדָבַ֣ק בְּאִשְׁתּ֔וֹ וְהָי֖וּ לְבָשָׂ֥ר אֶחָֽד׃
因此,男人要離開他的父親和母親,與他的妻子緊密結合,他們成為一體。
Rashi
על כן יעזב איש THEREFORE A MAN LEAVETH — The Divine Spirit says this, thus prohibiting immoral relationship to the “Sons of Noah” also (Sanhedrin 57b).
Ramban
THEREFORE SHALL A MAN LEAVE HIS FATHER AND HIS MOTHER, AND SHALL CLEAVE TO HIS WIFE. The Divine Spirit says this, thus prohibiting immoral relationships to “the sons of Noah.”372See above, Note 222.
Radak
על כן יעזב איש, some commentators believe that these words were spoken by Moses, not by Adam. The correct interpretation is that they were spoken by Adam, seeing that he was aware that he would father children, for this was why he had been created, in order to populate earth and ensure that his species would be perpetuated on earth, just as all the other species of living creatures. The plain meaning of our verse is close to the words of Targum Onkelos: על כן ישבוק גבר בית משכבי אבוהי ואמיה, “for this purpose a man will leave the house of his father and mother, etc.” The point of all this is that the Torah did not give permission for man to leave, move away from his parents, in order to devote himself to his wife instead, but in order to fulfill the commandment to found his own family, have children. Man is supposed to live in a separate dwelling, separate from that of his parents, in order to have and raise his children.