Midrash su Isaia 40:9

Sometime later R. Eliezer and R. Joshua met him and noticed that his countenance had changed. They said to each other: “Aquila must be studying the Torah.” When he drew near them, he asked numerous questions which they answered. Later he returned to his uncle, Hadrian, who asked him: “Why has your countenance changed? I am inclined to think that your business was unsuccessful or that some person oppressed you.” (He answered) “That is not so. You are my relative, and no man would dare oppress me.” Hadrian continued asking him: “But why has your countenance changed?” “I have studied the Torah,” he replied, “and I was also circumcised.” “Who advised you to do that?” he asked. “You did,” he answered. “When did I do that?” “When I told you I desired to engage in business, you said: ‘Whatever merchandise you find low, that is worthless, and lying on the ground because it is ignored, do business in it, for it will finally rise in value.’ I have traveled among the nations and have found nothing so low and so cast down as Israel, and it is destined to rise, as Isaiah said: Thus saith the Lord, the Redeemer of Israel, His Holy One, to him who is despised of men, to him who is abhorred of nations, to a servant of rulers: “Kings shall see and arise; princes, and they shall prostrate themselves; because of the Lord that is faithful, even the Holy One of Israel, who hath chosen thee” (Isa. 40:9). His advisor said to him: “Are these the ones about whom you spoke—will a king arise before them in the future, as it is said: Kings shall see and arise?” Hadrian struck him (the advisor) upon his cheek and shouted: “Now go dress that wound. If they saw just one legionary they would be unable to rise up against him, yet you dare say of them: Kings shall see and arise before them.”

Another interpretation (of Gen. 27:22): THE VOICE IS THE VOICE OF JACOB, BUT THE HANDS ARE THE HANDS OF ESAU. The hands of Esau shall be shaken when the voice of Jacob comes. This (coming voice of Jacob) refers to the Messianic King, according to what is stated (in Is. 40:9): GO UP UPON A HIGH MOUNTAIN, O HERALD OF GOOD TIDINGS TO ZION, RAISE YOUR VOICE WITH STRENGTH.