כִּ֤י אִם־עֲוֺנֹֽתֵיכֶם֙ הָי֣וּ מַבְדִּלִ֔ים בֵּינֵכֶ֕ם לְבֵ֖ין אֱלֹֽהֵיכֶ֑ם וְחַטֹּֽאותֵיכֶ֗ם הִסְתִּ֧ירוּ פָנִ֛ים מִכֶּ֖ם מִשְּׁמֽוֹעַ׃
Ma le tue iniquità si sono separate tra te e il tuo Dio, e i tuoi peccati ti hanno nascosto il volto da non sentire.
Targum Jonathan on Isaiah
But your iniquities separate between you and your God, and your sins have caused Him to take away the favour of His Shekinah from you, not to receive your prayer.